CSC Pharmaceuticals International




Holoxan Injection


Holoxan Injection

HOLOXAN (ifosfamide) New Zealand Data Sheet
HOLOXAN Data Sheet 10 December 2013 Page 1 of 23
Baxter
HOLOXAN
Ifosfamide 500mg, 1g, 2g Powder for Injection
FOR INTRAVENOUS USE ONLY
DESCRIPTION
HOLOXAN (sterile ifosfamide) is supplied as
single-dose vials of 500mg, 1g, or 2g for
reconstitution and administration by intrave
nous injection/infusion. Ifosfamide is a
chemotherapeutic agent related ch
emically to the nitrogen mustards
and is a synthetic analogue of
cyclophosphamide. Ifosfamide is 3-(2-chloroe
thyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-
oxazaphosphorine 2-oxide. The molecular formula is C
7
H
15
CI
2
N
2
O
2
P and its molecular weight is
261.1. Its structural formula is:
Ifosfamide is a white crystalline powder that is soluble in water




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