CSC Pharmaceuticals International




Endoxan Injection


Endoxan Injection

ENDOXAN (cyclophosphamide) New Zealand Data Sheet
27 February 2012 Page 1 of 26
Baxter
ENDOXAN
Cyclophosphamide powder for inj
ection, 500mg, 1.0g or 2.0g
NAME OF DRUG
ENDOXAN is available in 3 strengths: 500m
g, 1.0g or 2.0g of cyclophosphamide per vial.
DESCRIPTION
Cyclophosphamide is chemically 2-Bis (2-chl
oroethyl) aminoperhydro-1, 3, 2-oxazaphosphorine
2-oxide. It exists as the monohydrat
e. The chemical formula is C
7
H
15
Cl
2
N
2
O
2
P.H
2
O and its
molecular weight is 279.1. The CAS number is
6055-19-2 and the chemical structure is as
follows:
The white crystalline monohydrate is soluble
in water (> 4% w/v). Cyclophosphamide
monohydrate liquefies when its wate
r of crystallisation is lost.




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